Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN). [electronic resource]
Producer: 20170619Description: 8924-8940 p. digitalISSN:- 1520-4804
- Antineoplastic Agents -- chemistry
- Bexarotene
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- HEK293 Cells
- Histone Deacetylase 1 -- genetics
- Humans
- Lymphoma, T-Cell, Cutaneous -- drug therapy
- Models, Molecular
- Niacin -- analogs & derivatives
- Retinoid X Receptors -- agonists
- Sterol Regulatory Element Binding Proteins -- genetics
- Tetrahydronaphthalenes -- chemistry
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Publication Type: Journal Article
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