The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. [electronic resource]
Producer: 20171024Description: 51 p. digitalISSN:- 2051-5960
- Amyotrophic Lateral Sclerosis -- metabolism
- Animals
- Autophagy -- physiology
- Autophagy-Related Protein-1 Homolog -- metabolism
- Autophagy-Related Proteins
- C9orf72 Protein
- CRISPR-Cas Systems
- Carrier Proteins -- metabolism
- Frontotemporal Lobar Degeneration -- metabolism
- Guanine Nucleotide Exchange Factors -- genetics
- HEK293 Cells
- HeLa Cells
- Humans
- Intracellular Signaling Peptides and Proteins -- metabolism
- Liver -- metabolism
- Lymph Nodes -- metabolism
- Lysosomes -- metabolism
- Mice, Knockout
- Protein Binding
- Protein Multimerization
- Protein-Tyrosine Kinases -- metabolism
- Proteins -- metabolism
- Spleen -- metabolism
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Publication Type: Journal Article
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