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Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3). [electronic resource] by
- Flanagan, Jack U
- Atwell, Graham J
- Heinrich, Daniel M
- Brooke, Darby G
- Silva, Shevan
- Rigoreau, Laurent J M
- Trivier, Elisabeth
- Turnbull, Andrew P
- Raynham, Tony
- Jamieson, Stephen M F
- Denny, William A
Producer: 20141028
In:
Bioorganic & medicinal chemistry vol. 22
Availability: No items available.
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Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. [electronic resource] by
- Caldwell, John J
- Welsh, Emma J
- Matijssen, Cornelis
- Anderson, Victoria E
- Antoni, Laurent
- Boxall, Kathy
- Urban, Frederique
- Hayes, Angela
- Raynaud, Florence I
- Rigoreau, Laurent J M
- Raynham, Tony
- Aherne, G Wynne
- Pearl, Laurence H
- Oliver, Antony W
- Garrett, Michelle D
- Collins, Ian
Producer: 20110307
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
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3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. [electronic resource] by
- Jamieson, Stephen M F
- Brooke, Darby G
- Heinrich, Daniel
- Atwell, Graham J
- Silva, Shevan
- Hamilton, Emma J
- Turnbull, Andrew P
- Rigoreau, Laurent J M
- Trivier, Elisabeth
- Soudy, Christelle
- Samlal, Sharon S
- Owen, Paul J
- Schroeder, Ewald
- Raynham, Tony
- Flanagan, Jack U
- Denny, William A
Producer: 20121231
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase. [electronic resource] by
- Hollick, Jonathan J
- Rigoreau, Laurent J M
- Cano-Soumillac, Celine
- Cockcroft, Xiaoling
- Curtin, Nicola J
- Frigerio, Mark
- Golding, Bernard T
- Guiard, Sophie
- Hardcastle, Ian R
- Hickson, Ian
- Hummersone, Marc G
- Menear, Keith A
- Martin, Niall M B
- Matthews, Ian
- Newell, David R
- Ord, Rachel
- Richardson, Caroline J
- Smith, Graeme C M
- Griffin, Roger J
Producer: 20070618
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. [electronic resource] by
- Boyd, Scott
- Brookfield, Joanna L
- Critchlow, Susan E
- Cumming, Iain A
- Curtis, Nicola J
- Debreczeni, Judit
- Degorce, Sébastien L
- Donald, Craig
- Evans, Nicola J
- Groombridge, Sam
- Hopcroft, Philip
- Jones, Neil P
- Kettle, Jason G
- Lamont, Scott
- Lewis, Hilary J
- MacFaull, Philip
- McLoughlin, Sheila B
- Rigoreau, Laurent J M
- Smith, James M
- St-Gallay, Steve
- Stock, Julie K
- Turnbull, Andrew P
- Wheatley, Edward R
- Winter, Jon
- Wingfield, Jonathan
Producer: 20150629
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4. [electronic resource] by
- Myers, Stephanie M
- Miller, Duncan C
- Molyneux, Lauren
- Arasta, Mercedes
- Bawn, Ruth H
- Blackburn, Timothy J
- Cook, Simon J
- Edwards, Noel
- Endicott, Jane A
- Golding, Bernard T
- Griffin, Roger J
- Hammonds, Tim
- Hardcastle, Ian R
- Harnor, Suzannah J
- Heptinstall, Amy B
- Lochhead, Pamela A
- Martin, Mathew P
- Martin, Nick C
- Newell, David R
- Owen, Paul J
- Pang, Leon C
- Reuillon, Tristan
- Rigoreau, Laurent J M
- Thomas, Huw D
- Tucker, Julie A
- Wang, Lan-Zhen
- Wong, Ai-Ching
- Noble, Martin E M
- Wedge, Stephen R
- Cano, Celine
Producer: 20191002
In:
European journal of medicinal chemistry vol. 178
Availability: No items available.
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