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Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease. [electronic resource] by
- Frahm, Silke
- Melis, Valeria
- Horsley, David
- Rickard, Janet E
- Riedel, Gernot
- Fadda, Paula
- Scherma, Maria
- Harrington, Charles R
- Wischik, Claude M
- Theuring, Franz
- Schwab, Karima
Producer: 20180807
In:
Behavioural brain research vol. 339
Availability: No items available.
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Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking. [electronic resource] by
- Al-Hilaly, Youssra K
- Pollack, Saskia J
- Vadukul, Devkee M
- Citossi, Francesca
- Rickard, Janet E
- Simpson, Michael
- Storey, John M D
- Harrington, Charles R
- Wischik, Claude M
- Serpell, Louise C
Producer: 20171128
In:
Journal of molecular biology vol. 429
Availability: No items available.
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Cysteine-Independent Inhibition of Alzheimer's Disease-like Paired Helical Filament Assembly by Leuco-Methylthioninium (LMT). [electronic resource] by
- Al-Hilaly, Youssra K
- Pollack, Saskia J
- Rickard, Janet E
- Simpson, Michael
- Raulin, Ana-Caroline
- Baddeley, Thomas
- Schellenberger, Pascale
- Storey, John M D
- Harrington, Charles R
- Wischik, Claude M
- Serpell, Louise C
Producer: 20191003
In:
Journal of molecular biology vol. 430
Availability: No items available.
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Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain. [electronic resource] by
- Al-Hilaly, Youssra K
- Foster, Bronwen E
- Biasetti, Luca
- Lutter, Liisa
- Pollack, Saskia J
- Rickard, Janet E
- Storey, John M D
- Harrington, Charles R
- Xue, Wei-Feng
- Wischik, Claude M
- Serpell, Louise C
Producer: 20201005
In:
FEBS letters vol. 594
Availability: No items available.
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A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy. [electronic resource] by
- Schwab, Karima
- Frahm, Silke
- Horsley, David
- Rickard, Janet E
- Melis, Valeria
- Goatman, Elizabeth A
- Magbagbeolu, Mandy
- Douglas, Morag
- Leith, Michael G
- Baddeley, Thomas C
- Storey, John M D
- Riedel, Gernot
- Wischik, Claude M
- Harrington, Charles R
- Theuring, Franz
Publication details: Frontiers in molecular neuroscience 2017
In:
Frontiers in molecular neuroscience vol. 10
Availability: No items available.
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Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease. [electronic resource] by
- Harrington, Charles R
- Storey, John M D
- Clunas, Scott
- Harrington, Kathleen A
- Horsley, David
- Ishaq, Ahtsham
- Kemp, Steven J
- Larch, Christopher P
- Marshall, Colin
- Nicoll, Sarah L
- Rickard, Janet E
- Simpson, Michael
- Sinclair, James P
- Storey, Lynda J
- Wischik, Claude M
Producer: 20150728
In:
The Journal of biological chemistry vol. 290
Availability: No items available.
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Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models. [electronic resource] by
- Melis, Valeria
- Magbagbeolu, Mandy
- Rickard, Janet E
- Horsley, David
- Davidson, Kathleen
- Harrington, Kathleen A
- Goatman, Keith
- Goatman, Elizabeth A
- Deiana, Serena
- Close, Steve P
- Zabke, Claudia
- Stamer, Karsten
- Dietze, Silke
- Schwab, Karima
- Storey, John M D
- Harrington, Charles R
- Wischik, Claude M
- Theuring, Franz
- Riedel, Gernot
Producer: 20160113
In:
Behavioural pharmacology vol. 26
Availability: No items available.
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