Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia. [electronic resource]
Producer: 20180309Description: 2094-2097 p. digitalISSN:- 1476-5551
- Amino Acid Sequence
- Cell Proliferation
- Enzyme Inhibitors -- pharmacology
- Humans
- Leukemia, Myeloid, Acute -- metabolism
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- antagonists & inhibitors
- STAT5 Transcription Factor -- metabolism
- Sequence Homology, Amino Acid
- Syk Kinase -- antagonists & inhibitors
- fms-Like Tyrosine Kinase 3 -- chemistry
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Publication Type: Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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