Leishmanicidal effect of Spiranthera odoratíssima (Rutaceae) and its isolated alkaloid skimmianine occurs by a nitric oxide dependent mechanism. [electronic resource]
Producer: 20111222Description: 1224-33 p. digitalISSN:- 1469-8161
- Alkaloids -- chemistry
- Animals
- Antiprotozoal Agents -- chemistry
- Cells, Cultured
- Fruit -- chemistry
- Hexanes -- chemistry
- Humans
- Inhibitory Concentration 50
- Interleukin-10 -- antagonists & inhibitors
- Leishmania braziliensis -- cytology
- Leishmaniasis, Cutaneous -- drug therapy
- Life Cycle Stages -- drug effects
- Macrophages -- drug effects
- Mice
- Models, Molecular
- Nitric Oxide -- biosynthesis
- Nitric Oxide Synthase Type II -- chemistry
- Plant Extracts -- chemistry
- Quinolines -- chemistry
- Rutaceae -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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