The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors. [electronic resource]
Producer: 20040519Description: 21-30 p. digitalISSN:- 1540-658X
- Adrenergic beta-Antagonists -- pharmacology
- Arrestins -- metabolism
- Biological Assay
- Cell Line, Tumor
- Cells, Cultured
- DNA -- genetics
- Drug Evaluation, Preclinical
- Fluorescent Dyes
- Green Fluorescent Proteins
- Humans
- Image Processing, Computer-Assisted
- Ligands
- Luminescent Proteins -- metabolism
- Microscopy, Confocal
- Plasmids -- genetics
- Protein Binding
- Receptors, Adrenergic, beta-2 -- drug effects
- Receptors, G-Protein-Coupled -- physiology
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Publication Type: Journal Article
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