Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: role of the Akt/mTOR survival pathway and Bcl-2 family proteins. [electronic resource]
Producer: 20150821Description: 218-28 p. digitalISSN:- 1873-4596
- Adenosine Triphosphate -- metabolism
- Apoptosis -- drug effects
- Bile Acids and Salts -- pharmacology
- Cell Line, Tumor
- Cell Survival
- Genome, Mitochondrial -- physiology
- Humans
- Proto-Oncogene Proteins c-akt -- physiology
- Proto-Oncogene Proteins c-bcl-2 -- physiology
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- physiology
- TOR Serine-Threonine Kinases -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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