High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening. [electronic resource]
Producer: 20110929Description: e20114 p. digitalISSN:- 1932-6203
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Caspase 9 -- metabolism
- Caspases -- metabolism
- Cell Line, Tumor
- Chromatin -- metabolism
- Drug Resistance, Neoplasm -- drug effects
- Drug Screening Assays, Antitumor -- methods
- Fluorescence Resonance Energy Transfer
- High-Throughput Screening Assays -- methods
- Humans
- Imaging, Three-Dimensional
- Kinetics
- Membrane Potential, Mitochondrial -- drug effects
- Molecular Probes -- metabolism
- Peptide Hydrolases -- metabolism
- Reproducibility of Results
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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