Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis. [electronic resource]
Producer: 20071231Description: 359-66 p. digitalISSN:- 1438-2199
- Adenosine -- analogs & derivatives
- Adenosylmethionine Decarboxylase -- antagonists & inhibitors
- Animals
- Biogenic Polyamines -- biosynthesis
- Chagas Disease -- drug therapy
- Eflornithine -- therapeutic use
- Enzyme Inhibitors -- therapeutic use
- Glutathione -- analogs & derivatives
- Humans
- Leishmania -- drug effects
- Leishmaniasis -- drug therapy
- Ornithine Decarboxylase Inhibitors
- Robenidine -- analogs & derivatives
- Spermidine -- analogs & derivatives
- Spermidine Synthase -- antagonists & inhibitors
- Trypanocidal Agents -- pharmacokinetics
- Trypanosoma brucei gambiense -- drug effects
- Trypanosoma brucei rhodesiense -- drug effects
- Trypanosoma cruzi -- drug effects
- Trypanosomiasis, African -- drug therapy
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
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