Synthesis and evaluation of potent and selective beta(3) adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres. [electronic resource]
Producer: 20020219Description: 567-83 p. digitalISSN:- 0022-2623
- Adrenergic beta-Agonists -- chemical synthesis
- Aniline Compounds -- chemical synthesis
- Animals
- Biological Availability
- Body Temperature -- drug effects
- CHO Cells
- Chromatography, High Pressure Liquid
- Cricetinae
- Cyclic AMP -- biosynthesis
- Dogs
- Humans
- Magnetic Resonance Spectroscopy
- Male
- Mass Spectrometry
- Mice
- Radioligand Assay
- Receptors, Adrenergic, beta-3 -- drug effects
- Stereoisomerism
- Structure-Activity Relationship
- Sulfonamides -- chemical synthesis
- Sulfonylurea Compounds -- chemical synthesis
- Thermography
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Publication Type: Journal Article
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