Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib. [electronic resource]
Producer: 20120830Description: 2704-14 p. digitalISSN:- 1557-3265
- 3' Untranslated Regions -- genetics
- Animals
- Benzodioxoles -- pharmacology
- Biomarkers, Tumor -- genetics
- Cell Line, Tumor
- Class I Phosphatidylinositol 3-Kinases
- Colorectal Neoplasms -- drug therapy
- Drug Resistance, Neoplasm -- genetics
- Gene Dosage
- Gene Expression Profiling
- Humans
- Immunoblotting
- Immunoprecipitation
- Mice
- MicroRNAs -- genetics
- Mutation -- genetics
- Oligonucleotide Array Sequence Analysis
- PTEN Phosphohydrolase
- Phosphatidylinositol 3-Kinases -- genetics
- Quinazolines -- pharmacology
- Signal Transduction -- drug effects
- Xenograft Model Antitumor Assays
- src-Family Kinases -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.