The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries. [electronic resource]
Producer: 20120813Description: 980-9 p. digitalISSN:- 1473-5598
- Amides -- pharmacology
- Animals
- Blood Glucose -- metabolism
- Blood Pressure
- Endothelin-1 -- antagonists & inhibitors
- Enzyme Inhibitors -- pharmacology
- Humans
- Protein Isoforms
- Pyridines -- pharmacology
- RNA, Messenger -- metabolism
- Rats
- Rats, Zucker
- Renal Artery -- drug effects
- Species Specificity
- Vascular Resistance
- Vasoconstrictor Agents
- rho-Associated Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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