Synthesis and structure-activity relationships of lapacho analogues. 1. Suppression of human keratinocyte hyperproliferation by 2-substituted naphtho[2,3-b]furan-4,9-diones, activation by enzymatic one- and two-electron reduction, and intracellular generation of superoxide. [electronic resource]
Producer: 20121126Description: 7273-84 p. digitalISSN:- 1520-4804
- Cell Line
- Cell Membrane -- drug effects
- Cell Proliferation -- drug effects
- Dermatologic Agents -- chemical synthesis
- Dicumarol -- pharmacology
- Furans -- chemical synthesis
- Humans
- Keratinocytes -- cytology
- L-Lactate Dehydrogenase -- metabolism
- NAD(P)H Dehydrogenase (Quinone) -- antagonists & inhibitors
- NADPH-Ferrihemoprotein Reductase -- chemistry
- Naphthoquinones -- chemical synthesis
- Oxadiazoles -- chemical synthesis
- Psoriasis -- drug therapy
- Structure-Activity Relationship
- Superoxides -- chemistry
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Publication Type: Journal Article
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