Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site. [electronic resource]
Producer: 20040907Description: 573-85 p. digitalISSN:- 1470-8728
- Amino Acid Sequence
- Arrestins -- metabolism
- Cell Line
- Endocytosis -- drug effects
- Humans
- Ligands
- Molecular Sequence Data
- Mutation -- genetics
- Phosphopeptides -- chemistry
- Phosphorylation -- drug effects
- Prostaglandins -- pharmacology
- Protein Structure, Tertiary
- Receptors, Prostaglandin E -- agonists
- Receptors, Prostaglandin E, EP4 Subtype
- Serine -- genetics
- Signal Transduction -- drug effects
- Threonine -- genetics
- beta-Arrestins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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