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Optimisation of pharmacokinetic properties in a neutral series of 11β-HSD1 inhibitors. [electronic resource] by
- Scott, James S
- Gill, Adrian L
- Godfrey, Linda
- Groombridge, Sam D
- Rees, Amanda
- Revill, John
- Schofield, Paul
- Sörme, Pernilla
- Stocker, Andrew
- Swales, John G
- Whittamore, Paul R O
Producer: 20130320
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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5.
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Novel acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). [electronic resource] by
- Scott, James S
- deSchoolmeester, Joanne
- Kilgour, Elaine
- Mayers, Rachel M
- Packer, Martin J
- Hargreaves, David
- Gerhardt, Stefan
- Ogg, Derek J
- Rees, Amanda
- Selmi, Nidhal
- Stocker, Andrew
- Swales, John G
- Whittamore, Paul R O
Producer: 20130205
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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6.
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Structure-based design of protein tyrosine phosphatase-1B inhibitors. [electronic resource] by
- Black, Emma
- Breed, Jason
- Breeze, Alexander L
- Embrey, Kevin
- Garcia, Robert
- Gero, Thomas W
- Godfrey, Linda
- Kenny, Peter W
- Morley, Andrew D
- Minshull, Claire A
- Pannifer, Andrew D
- Read, Jon
- Rees, Amanda
- Russell, Daniel J
- Toader, Dorin
- Tucker, Julie
Producer: 20051011
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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7.
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Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: discovery of 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid (AZD4017). [electronic resource] by
- Scott, James S
- Bowker, Suzanne S
- Deschoolmeester, Joanne
- Gerhardt, Stefan
- Hargreaves, David
- Kilgour, Elaine
- Lloyd, Adele
- Mayers, Rachel M
- McCoull, William
- Newcombe, Nicholas J
- Ogg, Derek
- Packer, Martin J
- Rees, Amanda
- Revill, John
- Schofield, Paul
- Selmi, Nidhal
- Swales, John G
- Whittamore, Paul R O
Producer: 20120907
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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