Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin. [electronic resource]
Producer: 20131127Description: 279-89 p. digitalISSN:- 1768-3254
- Antineoplastic Agents -- chemical synthesis
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Crystallography, X-Ray
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Flow Cytometry
- G1 Phase -- drug effects
- Humans
- Inhibitory Concentration 50
- Isoxazoles -- chemical synthesis
- MCF-7 Cells
- Models, Chemical
- Molecular Conformation
- Molecular Structure
- Santonin -- chemical synthesis
- Stereoisomerism
- Transcription Factor RelA -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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