Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats. [electronic resource]
Producer: 20150511Description: 28 p. digitalISSN:- 2050-6511
- Animals
- Blood Glucose -- metabolism
- CHO Cells
- Carrier Proteins -- genetics
- Cell Cycle Proteins
- Cell Line, Tumor
- Cricetinae
- Cricetulus
- Diabetes Mellitus, Type 2 -- blood
- Disease Progression
- Drug Administration Schedule
- Fatty Acids, Nonesterified -- blood
- Fructosamine -- blood
- Gene Expression -- drug effects
- Glycated Hemoglobin -- metabolism
- Homeodomain Proteins -- genetics
- Hypoglycemic Agents -- pharmacology
- Immunohistochemistry
- Insulin -- blood
- Insulin-Secreting Cells -- drug effects
- Male
- Pharmaceutical Preparations
- Rats, Zucker
- Receptors, G-Protein-Coupled -- agonists
- Reverse Transcriptase Polymerase Chain Reaction
- Trans-Activators -- genetics
- Transcription Factor CHOP -- genetics
- Triglycerides -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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