Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells. [electronic resource]
Producer: 20150422Description: 1148-64 p. digitalISSN:- 1573-675X
- Alkaloids -- pharmacology
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Fragmentation -- drug effects
- Dioxolanes -- pharmacology
- Female
- Humans
- Molecular Docking Simulation
- Phosphatidylinositol 3-Kinase -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- TOR Serine-Threonine Kinases -- metabolism
- Triple Negative Breast Neoplasms -- metabolism
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Publication Type: Journal Article
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