Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues. [electronic resource]
Producer: 20180423Description: 30827 p. digitalISSN:- 2045-2322
- Aspartic Acid -- analogs & derivatives
- Bacterial Proteins -- antagonists & inhibitors
- Binding Sites
- Bridged-Ring Compounds -- chemistry
- Catalytic Domain
- Crystallography, X-Ray
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Hydro-Lyases -- antagonists & inhibitors
- Hydrogen Bonding
- Inhibitory Concentration 50
- Ketones -- chemistry
- Kinetics
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Mycobacterium tuberculosis -- drug effects
- Pyruvic Acid -- chemistry
- Recombinant Proteins -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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