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Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation. [electronic resource] by
- Goodwin, Nicole C
- Cianchetta, Giovanni
- Burgoon, Hugh A
- Healy, Jason
- Mabon, Ross
- Strobel, Eric D
- Allen, Jason
- Wang, Shuli
- Hamman, Brian D
- Rawlins, David B
Producer: 20150115
In:
ACS medicinal chemistry letters vol. 6
Availability: No items available.
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1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues. [electronic resource] by
- Misra, Raj N
- Xiao, Hai yun
- Rawlins, David B
- Shan, Weifang
- Kellar, Kristen A
- Mulheron, Janet G
- Sack, John S
- Tokarski, John S
- Kimball, S David
- Webster, Kevin R
Producer: 20040227
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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7.
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1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases. [electronic resource] by
- Misra, Raj N
- Rawlins, David B
- Xiao, Hai-yun
- Shan, Weifang
- Bursuker, Isia
- Kellar, Kristin A
- Mulheron, Janet G
- Sack, John S
- Tokarski, John S
- Kimball, S David
- Webster, Kevin R
Producer: 20031027
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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8.
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LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2. [electronic resource] by
- Powell, David R
- Smith, Melinda G
- Doree, Deon D
- Harris, Angela L
- Xiong, Wendy W
- Mseeh, Faika
- Wilson, Alan
- Gopinathan, Suma
- Diaz, Damaris
- Goodwin, Nicole C
- Harrison, Bryce
- Strobel, Eric
- Rawlins, David B
- Carson, Ken
- Zambrowicz, Brian
- Ding, Zhi-Ming
Producer: 20150603
In:
Pharmacology research & perspectives vol. 3
Availability: No items available.
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Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. [electronic resource] by
- Goodwin, Nicole C
- Mabon, Ross
- Harrison, Bryce A
- Shadoan, Melanie K
- Almstead, Zheng Y
- Xie, Yiling
- Healy, Jason
- Buhring, Lindsey M
- DaCosta, Christopher M
- Bardenhagen, Jennifer
- Mseeh, Faika
- Liu, Qingyun
- Nouraldeen, Amr
- Wilson, Alan G E
- Kimball, S David
- Powell, David R
- Rawlins, David B
Producer: 20091124
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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10.
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Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes. [electronic resource] by
- Goodwin, Nicole C
- Ding, Zhi-Ming
- Harrison, Bryce A
- Strobel, Eric D
- Harris, Angela L
- Smith, Melinda
- Thompson, Andrea Y
- Xiong, Wendy
- Mseeh, Faika
- Bruce, Debra J
- Diaz, Damaris
- Gopinathan, Suma
- Li, Ling
- O'Neill, Emily
- Thiel, Mary
- Wilson, Alan G E
- Carson, Kenneth G
- Powell, David R
- Rawlins, David B
Producer: 20170704
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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11.
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LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice. [electronic resource] by
- Powell, David R
- Smith, Melinda G
- Doree, Deon D
- Harris, Angela L
- Greer, Jennifer
- DaCosta, Christopher M
- Thompson, Andrea
- Jeter-Jones, Sabrina
- Xiong, Wendy
- Carson, Kenneth G
- Goodwin, Nicole C
- Harrison, Bryce A
- Rawlins, David B
- Strobel, Eric D
- Gopinathan, Suma
- Wilson, Alan
- Mseeh, Faika
- Zambrowicz, Brian
- Ding, Zhi-Ming
Producer: 20170621
In:
The Journal of pharmacology and experimental therapeutics vol. 362
Availability: No items available.
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12.
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Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma. [electronic resource] by
- Harrison, Bryce A
- Almstead, Zheng Y
- Burgoon, Hugh
- Gardyan, Michael
- Goodwin, Nicole C
- Healy, Jason
- Liu, Ying
- Mabon, Ross
- Marinelli, Brett
- Samala, Lakshman
- Zhang, Yulian
- Stouch, Terry R
- Whitlock, N Andrew
- Gopinathan, Suma
- McKnight, Beth
- Wang, Shuli
- Patel, Nita
- Wilson, Alan G E
- Hamman, Brian D
- Rice, Dennis S
- Rawlins, David B
Producer: 20150115
In:
ACS medicinal chemistry letters vol. 6
Availability: No items available.
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13.
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Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. [electronic resource] by
- Harrison, Bryce A
- Whitlock, N Andrew
- Voronkov, Michael V
- Almstead, Zheng Y
- Gu, Kun-jian
- Mabon, Ross
- Gardyan, Michael
- Hamman, Brian D
- Allen, Jason
- Gopinathan, Suma
- McKnight, Beth
- Crist, Mike
- Zhang, Yulian
- Liu, Ying
- Courtney, Lawrence F
- Key, Billie
- Zhou, Julia
- Patel, Nita
- Yates, Phil W
- Liu, Qingyun
- Wilson, Alan G E
- Kimball, S David
- Crosson, Craig E
- Rice, Dennis S
- Rawlins, David B
Producer: 20091215
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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14.
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Correction to N-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent. [electronic resource] by
- Misra, Raj N
- Xiao, Hai-yun
- Kim, Kyoung S
- Lu, Songfeng
- Han, Wen-Ching
- Barbosa, Stephanie A
- Hunt, John T
- Rawlins, David B
- Shan, Weifang
- Ahmed, Syed Z
- Qian, Ligang
- Chen, Bang-Chi
- Zhao, Rulin
- Bednarz, Mark S
- Kellar, Kristen A
- Mulheron, Janet G
- Batorsky, Roberta
- Roongta, Urvashi
- Kamath, Amrita
- Marathe, Punit
- Ranadive, Sunanda A
- Sack, John S
- Tokarski, John S
- Pavletich, Nikola P
- Lee, Francis Y F
- Webster, Kevin R
- Kimball, S David
Producer: 20151214
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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15.
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N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent. [electronic resource] by
- Misra, Raj N
- Xiao, Hai-yun
- Kim, Kyoung S
- Lu, Songfeng
- Han, Wen-Ching
- Barbosa, Stephanie A
- Hunt, John T
- Rawlins, David B
- Shan, Weifang
- Ahmed, Syed Z
- Qian, Ligang
- Chen, Bang-Chi
- Zhao, Rulin
- Bednarz, Mark S
- Kellar, Kristen A
- Mulheron, Janet G
- Batorsky, Roberta
- Roongta, Urvashi
- Kamath, Amrita
- Marathe, Punit
- Ranadive, Sunanda A
- Sack, John S
- Tokarski, John S
- Pavletich, Nikola P
- Lee, Francis Y F
- Webster, Kevin R
- Kimball, S David
Producer: 20040510
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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16.
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Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities. [electronic resource] by
- Kim, Kyoung Soon
- Kimball, S David
- Misra, Raj N
- Rawlins, David B
- Hunt, John T
- Xiao, Hai-Yun
- Lu, Songfeng
- Qian, Ligang
- Han, Wen-Ching
- Shan, Weifang
- Mitt, Toomas
- Cai, Zhen-Wei
- Poss, Michael A
- Zhu, Hong
- Sack, John S
- Tokarski, John S
- Chang, Chieh Ying
- Pavletich, Nikola
- Kamath, Amrita
- Humphreys, William G
- Marathe, Punit
- Bursuker, Isia
- Kellar, Kristen A
- Roongta, Urvashi
- Batorsky, Roberta
- Mulheron, Janet G
- Bol, David
- Fairchild, Craig R
- Lee, Francis Y
- Webster, Kevin R
Producer: 20020923
In:
Journal of medicinal chemistry vol. 45
Availability: No items available.
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