The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax. [electronic resource]
Producer: 20200526Description: 152247 p. digitalISSN:- 1879-3185
- Antifungal Agents -- toxicity
- Aromatase -- drug effects
- Aromatase Inhibitors -- toxicity
- Cell Line, Tumor
- Clotrimazole -- toxicity
- Dose-Response Relationship, Drug
- Endocrine Disruptors -- toxicity
- Fluconazole -- toxicity
- Gas Chromatography-Mass Spectrometry
- Humans
- Inhibitory Concentration 50
- Ketoconazole -- toxicity
- Miconazole -- toxicity
- Steroid 17-alpha-Hydroxylase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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