Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity. [electronic resource]
Producer: 20150612Description: 664-76 p. digitalISSN:- 1549-8719
- Animals
- Astrocytes -- metabolism
- Blood Flow Velocity
- Capillaries -- pathology
- Doxycycline -- pharmacology
- Erythrocyte Indices
- Genes, tat
- HIV-1 -- genetics
- Hemodynamics
- Male
- Mice
- Mice, Transgenic
- Microscopy, Fluorescence, Multiphoton
- Neocortex -- blood supply
- Neovascularization, Physiologic -- drug effects
- Pyramidal Cells -- pathology
- Recombinant Fusion Proteins -- toxicity
- Up-Regulation -- drug effects
- tat Gene Products, Human Immunodeficiency Virus -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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