Up-regulation of mismatch repair genes MSH6, PMS2 and MLH1 parallels development of genetic instability and is linked to tumor aggressiveness and early PSA recurrence in prostate cancer. [electronic resource]
Producer: 20170906Description: 19-27 p. digitalISSN:- 1460-2180
- Biomarkers, Tumor -- analysis
- Case-Control Studies
- DNA Mismatch Repair -- genetics
- DNA-Binding Proteins -- genetics
- Follow-Up Studies
- Genomic Instability
- Humans
- Immunoenzyme Techniques
- Lymphatic Metastasis
- Male
- Mismatch Repair Endonuclease PMS2 -- genetics
- MutL Protein Homolog 1 -- genetics
- Neoplasm Grading
- Neoplasm Recurrence, Local -- blood
- Neoplasm Staging
- Oncogene Proteins, Fusion -- genetics
- Prognosis
- Prostate-Specific Antigen -- blood
- Prostatectomy
- Prostatic Neoplasms -- blood
- Up-Regulation
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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