IGF-1 reverses the osteogenic inhibitory effect of dexamethasone on BMP9-induced osteogenic differentiation in mouse embryonic fibroblasts via PI3K/AKT/COX-2 pathway. [electronic resource]
Producer: 20191120Description: 105363 p. digitalISSN:- 1879-1220
- Animals
- Cell Line
- Cells, Cultured
- Cyclooxygenase 2 -- metabolism
- Dexamethasone -- adverse effects
- Female
- Fibroblasts -- cytology
- Glucocorticoids -- adverse effects
- Growth Differentiation Factor 2 -- metabolism
- Humans
- Insulin-Like Growth Factor I -- metabolism
- Mice
- Mice, Nude
- Osteogenesis -- drug effects
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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