Silibinin inhibits hypoxia-induced HIF-1α-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics. [electronic resource]
Producer: 20170905Description: 833-848 p. digitalISSN:- 1098-2744
- Animals
- Antineoplastic Agents -- administration & dosage
- Cell Hypoxia -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- In Vitro Techniques
- Lipogenesis -- drug effects
- Male
- Metabolomics -- methods
- Mice
- Neovascularization, Pathologic -- drug therapy
- Prostatic Neoplasms -- drug therapy
- Signal Transduction -- drug effects
- Silybin
- Silymarin -- administration & dosage
- Treatment Outcome
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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