Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats. [electronic resource]
Producer: 20180518Description: 280-291 p. digitalISSN:- 1950-6007
- Animals
- Apoptosis -- drug effects
- Berberine -- therapeutic use
- Chemical and Drug Induced Liver Injury -- metabolism
- Heme Oxygenase (Decyclizing) -- metabolism
- Male
- Methotrexate -- toxicity
- NF-E2-Related Factor 2 -- metabolism
- Oxidative Stress -- drug effects
- PPAR gamma -- metabolism
- Rats, Wistar
- Signal Transduction
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Publication Type: Journal Article
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