Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE)). [electronic resource]
Producer: 20100907Description: 1629-35 p. digitalISSN:- 1468-2060
- Adult
- Aged
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Murine-Derived
- Antirheumatic Agents -- administration & dosage
- Arthritis, Rheumatoid -- drug therapy
- Dose-Response Relationship, Drug
- Double-Blind Method
- Drug Therapy, Combination
- Female
- Humans
- Male
- Methotrexate -- adverse effects
- Middle Aged
- Rituximab
- Severity of Illness Index
- Treatment Outcome
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Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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