Enteric infection coupled with chronic Notch pathway inhibition alters colonic mucus composition leading to dysbiosis, barrier disruption and colitis. [electronic resource]
Producer: 20190411Description: e0206701 p. digitalISSN:- 1932-6203
- Animals
- Animals, Outbred Strains
- Citrobacter rodentium
- Colitis -- drug therapy
- Colon -- drug effects
- Dibenzazepines -- pharmacology
- Disease Models, Animal
- Dysbiosis -- drug therapy
- Enterobacteriaceae Infections -- drug therapy
- Enzyme Inhibitors -- pharmacology
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Knockout
- Mucus -- immunology
- Receptors, Notch -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Tight Junctions -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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