Perfluorooctanoic acid (PFOA) affects distinct molecular signalling pathways in human primary hepatocytes. [electronic resource]
Producer: 20150817Description: 53-62 p. digitalISSN:- 1879-3185
- Caprylates -- toxicity
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Chemical and Drug Induced Liver Injury -- etiology
- Cyclins -- genetics
- Dose-Response Relationship, Drug
- Estrogen Receptor alpha -- agonists
- Fluorocarbons -- toxicity
- Gene Expression Profiling -- methods
- Gene Expression Regulation
- Gene Regulatory Networks
- Hep G2 Cells
- Hepatocyte Nuclear Factor 4 -- antagonists & inhibitors
- Hepatocytes -- drug effects
- Humans
- Oligonucleotide Array Sequence Analysis
- PPAR alpha -- agonists
- PPAR gamma -- agonists
- Primary Cell Culture
- Proto-Oncogene Proteins c-fos -- genetics
- Proto-Oncogene Proteins c-jun -- genetics
- Signal Transduction -- drug effects
- Time Factors
- Transcription Factor AP-1 -- genetics
- Transcriptome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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