Carvedilol suppresses migration and invasion of malignant breast cells by inactivating Src involving cAMP/PKA and PKCδ signaling pathway. [electronic resource]
Producer: 20151120Description: 998-1003 p. digitalISSN:- 1998-4138
- Adrenergic alpha-1 Receptor Antagonists -- chemistry
- Apoptosis
- Breast Neoplasms -- drug therapy
- CSK Tyrosine-Protein Kinase
- Carbazoles -- chemistry
- Carvedilol
- Cell Death
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Drug Screening Assays, Antitumor
- Female
- Humans
- MCF-7 Cells
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Phosphorylation
- Propanolamines -- chemistry
- Protein Kinase C-delta -- metabolism
- RNA, Small Interfering -- metabolism
- Signal Transduction
- src-Family Kinases -- metabolism
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Publication Type: Journal Article
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