Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models. [electronic resource]
Producer: 20060928Description: 934-40 p. digitalISSN:- 0028-3908
- Analysis of Variance
- Animals
- Antidepressive Agents -- therapeutic use
- Behavior, Animal -- drug effects
- Benzophenanthridines
- Berberine Alkaloids -- pharmacokinetics
- CHO Cells
- Cricetinae
- Cricetulus
- Depression -- drug therapy
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Head Movements -- drug effects
- Hindlimb Suspension -- methods
- Inhibitory Concentration 50
- Male
- Mice
- Mice, Inbred BALB C
- Motor Activity -- drug effects
- Norepinephrine Plasma Membrane Transport Proteins -- metabolism
- Protein Binding -- drug effects
- Serotonin Plasma Membrane Transport Proteins -- metabolism
- Tetrazolium Salts
- Thiazoles
- Transfection -- methods
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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