The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction. [electronic resource]
Producer: 20201216Description: 407-422 p. digitalISSN:- 1536-4844
- Claudins -- metabolism
- Colon -- cytology
- Epithelial Cells -- drug effects
- HT29 Cells
- Humans
- Inflammatory Bowel Diseases -- metabolism
- Interferon-gamma -- toxicity
- Intestinal Mucosa -- metabolism
- Intestines -- cytology
- Janus Kinase Inhibitors -- pharmacology
- Permeability -- drug effects
- Piperidines -- pharmacology
- Pyrimidines -- pharmacology
- Tight Junction Proteins -- genetics
- Tight Junctions -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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