13-cis-retinoic acid induces apoptosis by modulating caspase-3, bcl-2, and p53 gene expression and regulates the activation of transcription factors in B16F-10 melanoma cells. [electronic resource]
Producer: 20080902Description: 197-207 p. digitalISSN:- 0731-8898
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- genetics
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cytokines -- metabolism
- Drug Screening Assays, Antitumor
- Gene Expression Regulation, Neoplastic -- drug effects
- Isotretinoin -- pharmacology
- Melanoma, Experimental -- drug therapy
- Mice
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Messenger -- metabolism
- Transcription Factors -- biosynthesis
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article
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