Antitumor Effect of Pomolic Acid in Acute Myeloid Leukemia Cells Involves Cell Death, Decreased Cell Growth and Topoisomerases Inhibition. [electronic resource]
Producer: 20190805Description: 1457-1468 p. digitalISSN:- 1875-5992
- Antineoplastic Agents -- chemical synthesis
- Cell Death -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- DNA Cleavage
- DNA Topoisomerases -- metabolism
- DNA, Neoplasm -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- HL-60 Cells
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Models, Molecular
- Molecular Conformation
- Oleanolic Acid -- analogs & derivatives
- Structure-Activity Relationship
- Topoisomerase Inhibitors -- chemical synthesis
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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