Specificity of human anti-variable heavy (VH ) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor-α receptor 1. [electronic resource]
Producer: 20160315Description: 139-48 p. digitalISSN:- 1365-2249
- Administration, Inhalation
- Administration, Intravenous
- Adult
- Aged
- Animals
- Antibodies, Monoclonal -- administration & dosage
- Antibody Specificity -- immunology
- Autoantibodies -- blood
- Cell Line
- Cell Line, Tumor
- Epitopes -- immunology
- Female
- Humans
- Immunoglobulin Heavy Chains -- immunology
- Immunoglobulin Variable Region -- immunology
- Interleukin-8 -- immunology
- Macaca fascicularis
- Male
- Middle Aged
- Protein Binding -- immunology
- Receptors, Tumor Necrosis Factor, Type I -- antagonists & inhibitors
- Time Factors
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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