RON receptor tyrosine kinase, a negative regulator of inflammation, inhibits HIV-1 transcription in monocytes/macrophages and is decreased in brain tissue from patients with AIDS. [electronic resource]
Producer: 20050114Description: 6864-72 p. digitalISSN:- 0022-1767
- AIDS Dementia Complex -- enzymology
- Adult
- Anti-HIV Agents -- pharmacology
- Brain -- enzymology
- Cell Line
- Chronic Disease
- Down-Regulation -- genetics
- Enzyme Repression -- immunology
- HIV-1 -- genetics
- Humans
- Inflammation Mediators -- antagonists & inhibitors
- Macrophages -- enzymology
- Middle Aged
- Monocytes -- enzymology
- NF-kappa B -- antagonists & inhibitors
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Repressor Proteins -- antagonists & inhibitors
- Transcription, Genetic -- immunology
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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