Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. [electronic resource]
Producer: 20141028Description: 1389-96 p. digitalISSN:- 1464-3405
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cyclin E -- metabolism
- Cyclin-Dependent Kinase 2 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p27 -- genetics
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Lactones -- chemical synthesis
- MCF-7 Cells
- NF-kappa B -- antagonists & inhibitors
- Oncogene Proteins -- metabolism
- Poly(ADP-ribose) Polymerases -- metabolism
- Structure-Activity Relationship
- Transcription, Genetic -- drug effects
- bcl-X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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