P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. [electronic resource]
Producer: 20030703Description: 13309-17 p. digitalISSN:- 0021-9258
- Adenosine Triphosphate -- analogs & derivatives
- Alzheimer Disease -- genetics
- Animals
- Animals, Newborn
- Calcium -- physiology
- Cerebral Cortex -- physiology
- Chromones -- pharmacology
- Disease Models, Animal
- Embryo, Mammalian
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Kinetics
- MAP Kinase Signaling System -- physiology
- Mice
- Mice, Transgenic
- Microglia -- drug effects
- Morpholines -- pharmacology
- NADPH Oxidases -- metabolism
- Neutrophils -- physiology
- Phosphoinositide-3 Kinase Inhibitors
- Pregnancy
- Rats
- Rats, Sprague-Dawley
- Receptors, Purinergic P2 -- physiology
- Receptors, Purinergic P2X7
- Superoxides -- metabolism
- Up-Regulation
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Publication Type: Journal Article
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