Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors. [electronic resource]
Producer: 20021001Description: 4128-39 p. digitalISSN:- 0022-2623
- 8-Hydroxy-2-(di-n-propylamino)tetralin -- pharmacology
- Animals
- Carrier Proteins -- antagonists & inhibitors
- Frontal Lobe -- drug effects
- Hippocampus -- drug effects
- Hypothermia -- chemically induced
- In Vitro Techniques
- Male
- Membrane Glycoproteins -- antagonists & inhibitors
- Membrane Transport Proteins
- Mice
- Models, Molecular
- Nerve Tissue Proteins
- Piperazines -- chemical synthesis
- Propane -- analogs & derivatives
- Radioligand Assay
- Rats
- Receptors, Serotonin -- chemistry
- Receptors, Serotonin, 5-HT1
- Serotonin -- metabolism
- Serotonin Antagonists -- chemical synthesis
- Serotonin Plasma Membrane Transport Proteins
- Serotonin Receptor Agonists -- chemical synthesis
- Selective Serotonin Reuptake Inhibitors -- chemical synthesis
- Stereoisomerism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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