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mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF. [electronic resource] by
- Hannan, Katherine M
- Brandenburger, Yves
- Jenkins, Anna
- Sharkey, Kerith
- Cavanaugh, Alice
- Rothblum, Lawrence
- Moss, Tom
- Poortinga, Gretchen
- McArthur, Grant A
- Pearson, Richard B
- Hannan, Ross D
Producer: 20031216
In:
Molecular and cellular biology vol. 23
Availability: No items available.
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MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation. [electronic resource] by
- Poortinga, Gretchen
- Hannan, Katherine M
- Snelling, Hayley
- Walkley, Carl R
- Jenkins, Anna
- Sharkey, Kerith
- Wall, Meaghan
- Brandenburger, Yves
- Palatsides, Manuela
- Pearson, Richard B
- McArthur, Grant A
- Hannan, Ross D
Producer: 20050614
In:
The EMBO journal vol. 23
Availability: No items available.
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Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models. [electronic resource] by
- Lee, Jue Er Amanda
- Mitchell, Naomi C
- Zaytseva, Olga
- Chahal, Arjun
- Mendis, Peter
- Cartier-Michaud, Amandine
- Parsons, Linda M
- Poortinga, Gretchen
- Levens, David L
- Hannan, Ross D
- Quinn, Leonie M
Producer: 20160408
In:
Nature communications vol. 6
Availability: No items available.
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7.
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Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth. [electronic resource] by
- Guo, Linna
- Zaysteva, Olga
- Nie, Zuqin
- Mitchell, Naomi C
- Amanda Lee, Jue Er
- Ware, Thomas
- Parsons, Linda
- Luwor, Rodney
- Poortinga, Gretchen
- Hannan, Ross D
- Levens, David L
- Quinn, Leonie M
Producer: 20170605
In:
Nucleic acids research vol. 44
Availability: No items available.
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8.
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S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila. [electronic resource] by
- Mitchell, Naomi C
- Tchoubrieva, Elissaveta B
- Chahal, Arjun
- Woods, Simone
- Lee, Amanda
- Lin, Jane I
- Parsons, Linda
- Jastrzebski, Katarzyna
- Poortinga, Gretchen
- Hannan, Katherine M
- Pearson, Richard B
- Hannan, Ross D
- Quinn, Leonie M
Producer: 20160531
In:
Cellular signalling vol. 27
Availability: No items available.
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9.
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UBF levels determine the number of active ribosomal RNA genes in mammals. [electronic resource] by
- Sanij, Elaine
- Poortinga, Gretchen
- Sharkey, Kerith
- Hung, Sandy
- Holloway, Timothy P
- Quin, Jaclyn
- Robb, Elysia
- Wong, Lee H
- Thomas, Walter G
- Stefanovsky, Victor
- Moss, Tom
- Rothblum, Lawrence
- Hannan, Katherine M
- McArthur, Grant A
- Pearson, Richard B
- Hannan, Ross D
Producer: 20090206
In:
The Journal of cell biology vol. 183
Availability: No items available.
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10.
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A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes. [electronic resource] by
- Sanij, Elaine
- Diesch, Jeannine
- Lesmana, Analia
- Poortinga, Gretchen
- Hein, Nadine
- Lidgerwood, Grace
- Cameron, Donald P
- Ellul, Jason
- Goodall, Gregory J
- Wong, Lee H
- Dhillon, Amardeep S
- Hamdane, Nourdine
- Rothblum, Lawrence I
- Pearson, Richard B
- Haviv, Izhak
- Moss, Tom
- Hannan, Ross D
Producer: 20150921
In:
Genome research vol. 25
Availability: No items available.
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11.
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Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation. [electronic resource] by
- Diesch, Jeannine
- Bywater, Megan J
- Sanij, Elaine
- Cameron, Donald P
- Schierding, William
- Brajanovski, Natalie
- Son, Jinbae
- Sornkom, Jirawas
- Hein, Nadine
- Evers, Maurits
- Pearson, Richard B
- McArthur, Grant A
- Ganley, Austen R D
- O'Sullivan, Justin M
- Hannan, Ross D
- Poortinga, Gretchen
Producer: 20200402
In:
Communications biology vol. 2
Availability: No items available.
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12.
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Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance. [electronic resource] by
- Martin, Claire A
- Cullinane, Carleen
- Kirby, Laura
- Abuhammad, Shatha
- Lelliott, Emily J
- Waldeck, Kelly
- Young, Richard J
- Brajanovski, Natalie
- Cameron, Donald P
- Walker, Rachael
- Sanij, Elaine
- Poortinga, Gretchen
- Hannan, Ross D
- Pearson, Richard B
- Hicks, Rodney J
- McArthur, Grant A
- Sheppard, Karen E
Producer: 20190109
In:
International journal of cancer vol. 142
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13.
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Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma. [electronic resource] by
- Devlin, Jennifer R
- Hannan, Katherine M
- Hein, Nadine
- Cullinane, Carleen
- Kusnadi, Eric
- Ng, Pui Yee
- George, Amee J
- Shortt, Jake
- Bywater, Megan J
- Poortinga, Gretchen
- Sanij, Elaine
- Kang, Jian
- Drygin, Denis
- O'Brien, Sean
- Johnstone, Ricky W
- McArthur, Grant A
- Hannan, Ross D
- Pearson, Richard B
Producer: 20161013
In:
Cancer discovery vol. 6
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14.
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First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study. [electronic resource] by
- Khot, Amit
- Brajanovski, Natalie
- Cameron, Donald P
- Hein, Nadine
- Maclachlan, Kylee H
- Sanij, Elaine
- Lim, John
- Soong, John
- Link, Emma
- Blombery, Piers
- Thompson, Ella R
- Fellowes, Andrew
- Sheppard, Karen E
- McArthur, Grant A
- Pearson, Richard B
- Hannan, Ross D
- Poortinga, Gretchen
- Harrison, Simon J
Producer: 20200805
In:
Cancer discovery vol. 9
Availability: No items available.
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15.
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The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence. [electronic resource] by
- Wall, Meaghan
- Poortinga, Gretchen
- Stanley, Kym L
- Lindemann, Ralph K
- Bots, Michael
- Chan, Christopher J
- Bywater, Megan J
- Kinross, Kathryn M
- Astle, Megan V
- Waldeck, Kelly
- Hannan, Katherine M
- Shortt, Jake
- Smyth, Mark J
- Lowe, Scott W
- Hannan, Ross D
- Pearson, Richard B
- Johnstone, Ricky W
- McArthur, Grant A
Producer: 20130620
In:
Cancer discovery vol. 3
Availability: No items available.
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16.
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AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer. [electronic resource] by
- Chan, Joanna C
- Hannan, Katherine M
- Riddell, Kim
- Ng, Pui Yee
- Peck, Abigail
- Lee, Rachel S
- Hung, Sandy
- Astle, Megan V
- Bywater, Megan
- Wall, Meaghan
- Poortinga, Gretchen
- Jastrzebski, Katarzyna
- Sheppard, Karen E
- Hemmings, Brian A
- Hall, Michael N
- Johnstone, Ricky W
- McArthur, Grant A
- Hannan, Ross D
- Pearson, Richard B
Producer: 20111219
In:
Science signaling vol. 4
Availability: No items available.
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17.
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Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling. [electronic resource] by
- Quin, Jaclyn
- Chan, Keefe T
- Devlin, Jennifer R
- Cameron, Donald P
- Diesch, Jeannine
- Cullinane, Carleen
- Ahern, Jessica
- Khot, Amit
- Hein, Nadine
- George, Amee J
- Hannan, Katherine M
- Poortinga, Gretchen
- Sheppard, Karen E
- Khanna, Kum Kum
- Johnstone, Ricky W
- Drygin, Denis
- McArthur, Grant A
- Pearson, Richard B
- Sanij, Elaine
- Hannan, Ross D
Producer: 20180223
In:
Oncotarget vol. 7
Availability: No items available.
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18.
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Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53. [electronic resource] by
- Bywater, Megan J
- Poortinga, Gretchen
- Sanij, Elaine
- Hein, Nadine
- Peck, Abigail
- Cullinane, Carleen
- Wall, Meaghan
- Cluse, Leonie
- Drygin, Denis
- Anderes, Kenna
- Huser, Nanni
- Proffitt, Chris
- Bliesath, Joshua
- Haddach, Mustapha
- Schwaebe, Michael K
- Ryckman, David M
- Rice, William G
- Schmitt, Clemens
- Lowe, Scott W
- Johnstone, Ricky W
- Pearson, Richard B
- McArthur, Grant A
- Hannan, Ross D
Producer: 20120917
In:
Cancer cell vol. 22
Availability: No items available.
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19.
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Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene. [electronic resource] by
- Lefebure, Marcus
- Tothill, Richard W
- Kruse, Elizabeth
- Hawkins, Edwin D
- Shortt, Jake
- Matthews, Geoffrey M
- Gregory, Gareth P
- Martin, Benjamin P
- Kelly, Madison J
- Todorovski, Izabela
- Doyle, Maria A
- Lupat, Richard
- Li, Jason
- Schroeder, Jan
- Wall, Meaghan
- Craig, Stuart
- Poortinga, Gretchen
- Cameron, Don
- Bywater, Megan
- Kats, Lev
- Gearhart, Micah D
- Bardwell, Vivian J
- Dickins, Ross A
- Hannan, Ross D
- Papenfuss, Anthony T
- Johnstone, Ricky W
Producer: 20181115
In:
Nature communications vol. 8
Availability: No items available.
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20.
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Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma. [electronic resource] by
- AbuHammad, Shatha
- Cullinane, Carleen
- Martin, Claire
- Bacolas, Zoe
- Ward, Teresa
- Chen, Huiqin
- Slater, Alison
- Ardley, Kerry
- Kirby, Laura
- Chan, Keefe T
- Brajanovski, Natalie
- Smith, Lorey K
- Rao, Aparna D
- Lelliott, Emily J
- Kleinschmidt, Margarete
- Vergara, Ismael A
- Papenfuss, Anthony T
- Lau, Peter
- Ghosh, Prerana
- Haupt, Sue
- Haupt, Ygal
- Sanij, Elaine
- Poortinga, Gretchen
- Pearson, Richard B
- Falk, Hendrik
- Curtis, David J
- Stupple, Paul
- Devlin, Mark
- Street, Ian
- Davies, Michael A
- McArthur, Grant A
- Sheppard, Karen E
Producer: 20200324
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 116
Availability: No items available.
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