Results
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Randomised Phase 2 study of maintenance linsitinib (OSI-906) in combination with erlotinib compared with placebo plus erlotinib after platinum-based chemotherapy in patients with advanced non-small cell lung cancer. [electronic resource] by
- Ciuleanu, Tudor-Eliade
- Ahmed, Samreen
- Kim, Joo-Hang
- Mezger, Jörg
- Park, Keunchil
- Thomas, Michael
- Chen, Jihong
- Poondru, Srinivasu
- VanTornout, Jan M
- Whitcomb, Debbie
- Blackhall, Fiona
Producer: 20170914
In:
British journal of cancer vol. 117
Availability: No items available.
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7.
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Identification of 3-amido-4-anilinoquinolines as potent and selective inhibitors of CSF-1R kinase. [electronic resource] by
- Scott, David A
- Balliet, Carrie L
- Cook, Donald J
- Davies, Audrey M
- Gero, Thomas W
- Omer, Charles A
- Poondru, Srinivasu
- Theoclitou, Maria-Elena
- Tyurin, Boris
- Zinda, Michael J
Producer: 20100706
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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8.
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A phase I study of continuous oral dosing of OSI-906, a dual inhibitor of insulin-like growth factor-1 and insulin receptors, in patients with advanced solid tumors. [electronic resource] by
- Puzanov, Igor
- Lindsay, Colin R
- Goff, Laura
- Sosman, Jeff
- Gilbert, Jill
- Berlin, Jordan
- Poondru, Srinivasu
- Simantov, Ronit
- Gedrich, Rich
- Stephens, Andrew
- Chan, Emily
- Evans, T R Jeffry
Producer: 20151209
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 21
Availability: No items available.
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9.
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Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors. [electronic resource] by
- Macaulay, Valentine M
- Middleton, Mark R
- Eckhardt, S Gail
- Rudin, Charles M
- Juergens, Rosalyn A
- Gedrich, Richard
- Gogov, Sven
- McCarthy, Sean
- Poondru, Srinivasu
- Stephens, Andrew W
- Gadgeel, Shirish M
Producer: 20180131
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
Availability: No items available.
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10.
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Phase I study of intermittent oral dosing of the insulin-like growth factor-1 and insulin receptors inhibitor OSI-906 in patients with advanced solid tumors. [electronic resource] by
- Jones, Robin L
- Kim, Edward S
- Nava-Parada, Pilar
- Alam, Salma
- Johnson, Faye M
- Stephens, Andrew W
- Simantov, Ronit
- Poondru, Srinivasu
- Gedrich, Rich
- Lippman, Scott M
- Kaye, Stan B
- Carden, Craig P
Producer: 20151209
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 21
Availability: No items available.
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11.
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Phase 2 study evaluating intermittent and continuous linsitinib and weekly paclitaxel in patients with recurrent platinum resistant ovarian epithelial cancer. [electronic resource] by
- Oza, Amit
- Kaye, Stanley
- Van Tornout, Jan
- Sessa, Cristiana
- Gore, Martin
- Naumann, R Wendel
- Hirte, Hal
- Colombo, Nicoletta
- Chen, Jihong
- Gorla, Seema
- Poondru, Srinivasu
- Singh, Margaret
- Steinberg, Joyce
- Yuen, Geoff
- Banerjee, Susana
Producer: 20180709
In:
Gynecologic oncology vol. 149
Availability: No items available.
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12.
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A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations. [electronic resource] by
- Yu, Helena A
- Spira, Alexander
- Horn, Leora
- Weiss, Jared
- West, Howard
- Giaccone, Giuseppe
- Evans, Tracey
- Kelly, Ronan J
- Desai, Bhardwaj
- Krivoshik, Andrew
- Moran, Diarmuid
- Poondru, Srinivasu
- Jie, Fei
- Aoyama, Kouji
- Keating, Anne
- Oxnard, Geoffrey R
Producer: 20180801
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 23
Availability: No items available.
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13.
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A first in man, dose-finding study of the mTORC1/mTORC2 inhibitor OSI-027 in patients with advanced solid malignancies. [electronic resource] by
- Mateo, Joaquin
- Olmos, David
- Dumez, Herlinde
- Poondru, Srinivasu
- Samberg, Nancy L
- Barr, Sharon
- Van Tornout, Jan M
- Jie, Fei
- Sandhu, Shahneen
- Tan, Daniel S
- Moreno, Victor
- LoRusso, Patricia M
- Kaye, Stan B
- Schöffski, Patrick
Producer: 20160824
In:
British journal of cancer vol. 114
Availability: No items available.
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14.
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Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study. [electronic resource] by
- Fassnacht, Martin
- Berruti, Alfredo
- Baudin, Eric
- Demeure, Michael J
- Gilbert, Jill
- Haak, Harm
- Kroiss, Matthias
- Quinn, David I
- Hesseltine, Elizabeth
- Ronchi, Cristina L
- Terzolo, Massimo
- Choueiri, Toni K
- Poondru, Srinivasu
- Fleege, Tanya
- Rorig, Ramona
- Chen, Jihong
- Stephens, Andrew W
- Worden, Francis
- Hammer, Gary D
Producer: 20150629
In:
The Lancet. Oncology vol. 16
Availability: No items available.
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15.
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Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity. [electronic resource] by
- Lyne, Paul D
- Aquila, Brian
- Cook, Donald J
- Dakin, Les A
- Ezhuthachan, Jay
- Ioannidis, Stephanos
- Pontz, Timothy
- Su, Mei
- Ye, Qing
- Zheng, Xiaolan
- Block, Michael H
- Cowen, Scott
- Deegan, Tracy L
- Lee, John W
- Scott, David A
- Custeau, Dominique
- Drew, Lisa
- Poondru, Srinivasu
- Shen, Minhui
- Wu, Allan
Producer: 20100706
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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16.
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Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations. [electronic resource] by
- Leighl, Natasha B
- Rizvi, Naiyer A
- de Lima, Lopes Gilberto
- Arpornwirat, Wichit
- Rudin, Charles M
- Chiappori, Alberto A
- Ahn, Myung-Ju
- Chow, Laura Q M
- Bazhenova, Lyudmila
- Dechaphunkul, Arunee
- Sunpaweravong, Patrapim
- Eaton, Keith
- Chen, Jihong
- Medley, Sonja
- Poondru, Srinivasu
- Singh, Margaret
- Steinberg, Joyce
- Juergens, Rosalyn A
- Gadgeel, Shirish M
Producer: 20170926
In:
Clinical lung cancer vol. 18
Availability: No items available.
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17.
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First-in-human phase I trial of two schedules of OSI-930, a novel multikinase inhibitor, incorporating translational proof-of-mechanism studies. [electronic resource] by
- Yap, Timothy A
- Arkenau, Hendrik-Tobias
- Camidge, D Ross
- George, Suzanne
- Serkova, Natalie J
- Gwyther, Stephen J
- Spratlin, Jennifer L
- Lal, Rohit
- Spicer, James
- Desouza, Nandita M
- Leach, Martin O
- Chick, Jon
- Poondru, Srinivasu
- Boinpally, Ramesh
- Gedrich, Richard
- Brock, Katie
- Stephens, Andrew
- Eckhardt, S Gail
- Kaye, Stan B
- Demetri, George
- Scurr, Michelle
Producer: 20130930
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 19
Availability: No items available.
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18.
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Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. [electronic resource] by
- Aronov, Alex M
- Tang, Qing
- Martinez-Botella, Gabriel
- Bemis, Guy W
- Cao, Jingrong
- Chen, Guanjing
- Ewing, Nigel P
- Ford, Pamella J
- Germann, Ursula A
- Green, Jeremy
- Hale, Michael R
- Jacobs, Marc
- Janetka, James W
- Maltais, Francois
- Markland, William
- Namchuk, Mark N
- Nanthakumar, Suganthini
- Poondru, Srinivasu
- Straub, Judy
- ter Haar, Ernst
- Xie, Xiaoling
Producer: 20091124
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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