The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain. [electronic resource]
Producer: 20010510Description: 10366-73 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Amyloid Precursor Protein Secretases
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Baculoviridae -- metabolism
- Binding Sites
- Catalysis
- Cell Line
- Concanavalin A -- pharmacology
- Culture Media, Conditioned -- metabolism
- DNA, Complementary -- metabolism
- Dose-Response Relationship, Drug
- Electrophoresis, Polyacrylamide Gel
- Endopeptidases -- metabolism
- Furin
- Guanidine -- metabolism
- Humans
- Immunoblotting
- Insecta
- Kinetics
- Molecular Sequence Data
- Precipitin Tests
- Protein Denaturation
- Protein Folding
- Protein Precursors -- chemistry
- Protein Structure, Tertiary
- Recombinant Proteins -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Subtilisins -- pharmacology
- Time Factors
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Publication Type: Journal Article
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