A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. [electronic resource]
Producer: 19990210Description: 336-41 p. digitalISSN:- 0008-5472
- 3T3 Cells
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Antineoplastic Agents -- pharmacology
- Cell Differentiation -- drug effects
- Cyclooxygenase 2
- Dose-Response Relationship, Drug
- Humans
- Isoenzymes -- drug effects
- Membrane Proteins
- Mice
- Nitric Oxide Synthase -- antagonists & inhibitors
- Nitric Oxide Synthase Type II
- Oleanolic Acid -- analogs & derivatives
- Prostaglandin-Endoperoxide Synthases -- drug effects
- Rats
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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