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	1.	Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor. [electronic resource] by Wong, Pancras C Pinto, Donald J P Zhang, Donglu Producer: 20110902 In: Journal of thrombosis and thrombolysis vol. 31 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	2.	The emergence of factor Xa inhibitors for the treatment of cardiovascular diseases: a patent review. [electronic resource] by Pinto, Donald J P Qiao, Jennifer X Knabb, Robert M Producer: 20121016 In: Expert opinion on therapeutic patents vol. 22 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	3.	Nonpeptide factor Xa inhibitors: DPC423, a highly potent and orally bioavailable pyrazole antithrombotic agent. [electronic resource] by Wong, Pancras C Pinto, Donald J P Knabb, Robert M Producer: 20021105 In: Cardiovascular drug reviews vol. 20 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	4.	Apixaban inhibition of factor Xa: Microscopic rate constants and inhibition mechanism in purified protein systems and in human plasma. [electronic resource] by Luettgen, Joseph M Knabb, Robert M He, Kan Pinto, Donald J P Rendina, Alan R Producer: 20111230 In: Journal of enzyme inhibition and medicinal chemistry vol. 26 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	5.	Factor Xa inhibitors: next-generation antithrombotic agents. [electronic resource] by Pinto, Donald J P Smallheer, Joanne M Cheney, Daniel L Knabb, Robert M Wexler, Ruth R Producer: 20100930 In: Journal of medicinal chemistry vol. 53 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	6.	Effect of lung volume reduction surgery on diaphragmatic neuromechanical coupling at 2 years. [electronic resource] by Laghi, Franco Jubran, Amal Topeli, Arzu Fahey, Patrick J Garrity, Edward R de Pinto, Donald J Tobin, Martin J Producer: 20040713 In: Chest vol. 125 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	7.	Sulfation of o-demethyl apixaban: enzyme identification and species comparison. [electronic resource] by Wang, Lifei Raghavan, Nirmala He, Kan Luettgen, Joseph M Humphreys, W Griffith Knabb, Robert M Pinto, Donald J Zhang, Donglu Producer: 20090714 In: Drug metabolism and disposition: the biological fate of chemicals vol. 37 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	8.	A double antibody radioimmunoassay for the determination of XV459, the active hydrolysis metabolite of roxifiban, in human plasma. [electronic resource] by Pieniaszek, Henry J Davidson, Anna F Walton, Harry L Pinto, Donald J Olson, Richard E Reilly, Thomas M Barrett, Yu Chen Producer: 20030711 In: Journal of pharmaceutical and biomedical analysis vol. 30 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	9.	Disposition of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'- (methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)- 1H-pyrazole-5-carboxamide (DPC 423) by novel metabolic pathways. Characterization of unusual metabolites by liquid chromatography/mass spectrometry and NMR. [electronic resource] by Mutlib, Abdul E Shockcor, John Chen, Shiang-Yuan Espina, Robert J Pinto, Donald J Orwat, Michael J Prakash, Shimoga R Gan, Liang-Shang Producer: 20020322 In: Chemical research in toxicology vol. 15 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	10.	Factor XIa Inhibitors as New Anticoagulants. [electronic resource] by Quan, Mimi L Pinto, Donald J P Smallheer, Joanne M Ewing, William R Rossi, Karen A Luettgen, Joseph M Seiffert, Dietmar A Wexler, Ruth R Producer: 20190930 In: Journal of medicinal chemistry vol. 61 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	11.	Apixaban metabolism and pharmacokinetics after oral administration to humans. [electronic resource] by Raghavan, Nirmala Frost, Charles E Yu, Zhigang He, Kan Zhang, Haiying Humphreys, W Griffith Pinto, Donald Chen, Shiangyuan Bonacorsi, Samuel Wong, Pancras C Zhang, Donglu Producer: 20090302 In: Drug metabolism and disposition: the biological fate of chemicals vol. 37 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	12.	Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits. [electronic resource] by Wong, Pancras C Crain, Earl J Watson, Carol A Zaspel, Alverna M Wright, Matthew R Lam, Patrick Y Pinto, Donald J P Wexler, Ruth R Knabb, Robert M Producer: 20021224 In: The Journal of pharmacology and experimental therapeutics vol. 303 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	13.	Orally bioavailable factor Xa inhibitors containing alpha-substituted gem-dimethyl P4 moieties. [electronic resource] by Orwat, Michael J Qiao, Jennifer X He, Kan Rendina, Alan R Luettgen, Joseph M Rossi, Karen A Xin, Baomin Knabb, Robert M Wexler, Ruth R Lam, Patrick Y S Pinto, Donald J P Producer: 20150305 In: Bioorganic & medicinal chemistry letters vol. 24 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	14.	Preclinical pharmacokinetics and pharmacodynamics of apixaban, a potent and selective factor Xa inhibitor. [electronic resource] by He, Kan Luettgen, Joseph M Zhang, Donglu He, Bing Grace, James E Xin, Baomin Pinto, Donald J P Wong, Pancras C Knabb, Robert M Lam, Patrick Y S Wexler, Ruth R Grossman, Scott J Producer: 20111213 In: European journal of drug metabolism and pharmacokinetics vol. 36 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	15.	Phenyltriazolinones as potent factor Xa inhibitors. [electronic resource] by Quan, Mimi L Pinto, Donald J P Rossi, Karen A Sheriff, Steven Alexander, Richard S Amparo, Eugene Kish, Kevin Knabb, Robert M Luettgen, Joseph M Morin, Paul Smallwood, Angela Woerner, Francis J Wexler, Ruth R Producer: 20100602 In: Bioorganic & medicinal chemistry letters vol. 20 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	16.	Pyrazole-based factor Xa inhibitors containing N-arylpiperidinyl P4 residues. [electronic resource] by Qiao, Jennifer X Cheng, Xuhong Smallheer, Joanne M Galemmo, Robert A Drummond, Spencer Pinto, Donald J P Cheney, Daniel L He, Kan Wong, Pancras C Luettgen, Joseph M Knabb, Robert M Wexler, Ruth R Lam, Patrick Y S Producer: 20070515 In: Bioorganic & medicinal chemistry letters vol. 17 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	17.	Structure-activity relationship and pharmacokinetic profile of 5-ketopyrazole factor Xa inhibitors. [electronic resource] by Varnes, Jeffrey G Wacker, Dean A Pinto, Donald J P Orwat, Michael J Theroff, Jay P Wells, Brian Galemo, Robert A Luettgen, Joseph M Knabb, Robert M Bai, Steven He, Kan Lam, Patrick Y S Wexler, Ruth R Producer: 20080527 In: Bioorganic & medicinal chemistry letters vol. 18 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	18.	Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. [electronic resource] by Pinto, Donald J P Orwat, Michael J Koch, Stephanie Rossi, Karen A Alexander, Richard S Smallwood, Angela Wong, Pancras C Rendina, Alan R Luettgen, Joseph M Knabb, Robert M He, Kan Xin, Baomin Wexler, Ruth R Lam, Patrick Y S Producer: 20071206 In: Journal of medicinal chemistry vol. 50 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	19.	Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker. [electronic resource] by Corte, James R Fang, Tianan Osuna, Honey Pinto, Donald J P Rossi, Karen A Myers, Joseph E Sheriff, Steven Lou, Zhen Zheng, Joanna J Harper, Timothy W Bozarth, Jeffrey M Wu, Yiming Luettgen, Joseph M Seiffert, Dietmar A Decicco, Carl P Wexler, Ruth R Quan, Mimi L Producer: 20170706 In: Journal of medicinal chemistry vol. 60 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	20.	Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor. [electronic resource] by Quan, Mimi L Lam, Patrick Y S Han, Qi Pinto, Donald J P He, Ming Y Li, Renhua Ellis, Christopher D Clark, Charles G Teleha, Christopher A Sun, Jung-Hui Alexander, Richard S Bai, Steve Luettgen, Joseph M Knabb, Robert M Wong, Pancras C Wexler, Ruth R Producer: 20050503 In: Journal of medicinal chemistry vol. 48 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)

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Your search returned 32 results.