Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice. [electronic resource]
Producer: 20110111Description: e9777 p. digitalISSN:- 1932-6203
- Animals
- Anti-Anxiety Agents -- pharmacology
- Antidepressive Agents -- pharmacology
- Brain -- pathology
- Brain Diseases
- Brain-Derived Neurotrophic Factor -- metabolism
- Electrophysiology
- Enzyme-Linked Immunosorbent Assay -- methods
- Long-Term Potentiation
- Male
- Mice
- Neurons -- metabolism
- PC12 Cells
- Peptides, Cyclic -- chemistry
- Phosphorylation
- Rats
- Rats, Sprague-Dawley
- Receptor, trkB -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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