Potentiation of 2'-deoxyguanosine cytotoxicity by a novel inhibitor of purine nucleoside phosphorylase, 8-amino-9-benzylguanine. [electronic resource]
Producer: 19860220Description: 519-23 p. digitalISSN:- 0008-5472
- Antimetabolites, Antineoplastic -- chemical synthesis
- Cell Line
- Cell Survival -- drug effects
- Deoxyguanosine -- administration & dosage
- Drug Synergism
- Guanine -- administration & dosage
- Humans
- Kinetics
- Lymphocytes
- Pentosyltransferases -- antagonists & inhibitors
- Purine-Nucleoside Phosphorylase -- antagonists & inhibitors
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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