PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment. [electronic resource]
Producer: 20171116Description: e539 p. digitalISSN:- 2044-5385
- Animals
- Apoptosis
- Cell Adhesion
- Cell Line, Tumor
- Cell Movement
- Cell Proliferation
- Cell Survival -- genetics
- Class I Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
- Class Ib Phosphatidylinositol 3-Kinase -- metabolism
- Disease Models, Animal
- Heterografts
- Humans
- Interleukin-6 -- metabolism
- Mice
- Multiple Myeloma -- drug therapy
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Protein Isoforms
- Protein Subunits
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- Tumor Microenvironment
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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