Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. [electronic resource]
Producer: 20171201Description: 154-161 p. digitalISSN:- 1873-3913
- Breast Neoplasms -- enzymology
- Drug Resistance, Neoplasm -- drug effects
- Estrogens -- pharmacology
- Female
- Humans
- MCF-7 Cells
- Models, Biological
- Phenotype
- Phosphorylation -- drug effects
- Phosphoserine -- metabolism
- Protein Kinase Inhibitors -- pharmacology
- Signal Transduction -- drug effects
- Tamoxifen -- pharmacology
- Up-Regulation -- drug effects
- p21-Activated Kinases -- antagonists & inhibitors
- rac1 GTP-Binding Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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