Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach. [electronic resource]
Producer: 20121113Description: 376-80 p. digitalISSN:- 1365-2125
- Adenosine Triphosphate -- metabolism
- Adult
- Dose-Response Relationship, Drug
- Female
- Genotype
- Heterozygote
- Homozygote
- Humans
- Interleukin-1beta -- pharmacology
- Leukocytes -- drug effects
- Lipopolysaccharides -- pharmacology
- Male
- Middle Aged
- Phenotype
- Polymorphism, Single Nucleotide
- Prospective Studies
- Purinergic P2X Receptor Antagonists -- pharmacology
- Pyrrolidines -- pharmacology
- Receptors, Purinergic P2X7 -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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